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Rabbit Anti-Centrin 1/FITC Conjugated antibody
background:
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jul 2008]
Function:
Plays a fundamental role in microtubule-organizing center structure and function.
Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Centrosome of interphase and mitotic cells.
Similarity:
Belongs to the centrin family.
Contains 4 EF-hand domains.
Database links:
Entrez Gene: 1068 Human
Entrez Gene: 26369 Mouse
Omim: 603187 Human
SwissProt: Q12798 Human
SwissProt: P41209 Mouse
Unigene: 122511 Human
Unigene: 195831 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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