Home > Product > Antibody > Rabbit Anti-CRYL1/FITC Conjugated antibody
CRY; CRYL 1; Crystallin lambda 1; GDH; Gul3DH; L gulonate 3 dehydrogenase; Lambda CRY; Lambda crystallin homolog; MGC149525; MGC149526.
Cat:
SL14079R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,)
Immunogen:
KLH conjugated synthetic peptide derived from human CRYL1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
35kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]

Function:
CRYL1 is involved in the uronate cycle which functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. CRYL1 catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Widely expressed, with highest levels in liver and kidney.

Similarity:
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Database links:

Entrez Gene: 51084 Human

Entrez Gene: 68631 Mouse

Omim: 609877 Human

SwissProt: Q9Y2S2 Human

SwissProt: Q99KP3 Mouse

Unigene: 370703 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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