Rabbit Anti-PDE3B/FITC Conjugated antibody

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5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodie

Cat:

SL8621R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human PDE3B

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

124kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

Function:
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.

Subcellular Location:
Membrane.

Tissue Specificity:
Abundant in adipose tissues.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.

Database links:

Entrez Gene: 5140 Human

Entrez Gene: 18576 Mouse

Entrez Gene: 29516 Rat

Omim: 602047 Human

SwissProt: Q13370 Human

SwissProt: Q61409 Mouse

SwissProt: Q8CIX5 Mouse

SwissProt: Q63085 Rat

Unigene: 445711 Human

Unigene: 430730 Mouse

Unigene: 10322 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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