Rabbit Anti-HLA Class 1 ABC /HLA ABC/FITC Conjugated antibody

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1A01_HUMAN; HLA A; HLA B; HLA C; HLAabc; HLA class 1 A; HLA class 1 B; HLA class 1 C; Major histocompatibility complex, class I, A + B + C; MHC class I HLA A; MHC class I HLA B; MHC class I HLA C; MHC HLA ABC.

Cat:

SL10634R-FITC

Species Reactivity：

Human,

Immunogen：

KLH conjugated synthetic peptide derived from human HLA Class 1 ABC

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

38kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Involved in the presentation of foreign antigens to the immune system.

Subunit:
Dimer of alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein (By similarity).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Post-translational modifications:
Sulfated.
Polyubiquitinated in a post ER compartment through interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).

Similarity:
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 3105 Human

Omim: 142800 Human

SwissProt: P04439 Human

Unigene: 181244 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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