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Rabbit Anti-phospho-ETS2 (Thr72)/FITC Conjugated antibody
background:
This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Function:
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.
Database links:
Entrez Gene: 2114 Human
Entrez Gene: 23872 Mouse
Entrez Gene: 304063 Rat
Omim: 164740 Human
SwissProt: P15036 Human
SwissProt: P15037 Mouse
Unigene: 644231 Human
Unigene: 290207 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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