background:
Aspartyl-tRNA synthetase (DARS) is part of a multienzyme complex of aminoacyl-tRNA synthetases. Aspartyl-tRNA synthetase charges its cognate tRNA with aspartate during protein biosynthesis. [provided by RefSeq, Jul 2008]
Function:
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the class-II aminoacyl-tRNA synthetase family.
Database links:
Entrez Gene: 1615 Human
Entrez Gene: 510162 Cow
Entrez Gene: 226414 Mouse
Entrez Gene: 116483 Rat
Omim: 603084 Human
SwissProt: Q3SYZ4 Cow
SwissProt: P14868 Human
SwissProt: Q922B2 Mouse
SwissProt: P15178 Rat
Unigene: 503787 Human
Unigene: 28693 Mouse
Unigene: 431446 Mouse
Unigene: 2388 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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