background:
DDI1 is a 396 amino acid protein that contains one ubiquitin-like domain. The gene encoding DDI1 maps to human chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene.
Similarity:
Belongs to the DDI1 family.
Contains 1 ubiquitin-like domain.
Database links:
Entrez Gene: 414301 Human
Entrez Gene: 71829 Mouse
Entrez Gene: 367012 Rat
SwissProt: Human
SwissProt: Q8WTU0 Human
SwissProt: Q9DAF3 Mouse
SwissProt: A0JPP7 Rat
Unigene: 591941 Human
Unigene: 141452 Mouse
Unigene: 92290 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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