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Rabbit Anti-DDX41/FITC Conjugated antibody
background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression. [provided by RefSeq, Jul 2008]
Function:
Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing.
Subcellular Location:
Nucleus
Similarity:
Belongs to the DEAD box helicase family. DDX41 subfamily.
Contains 1 CCHSLCtype zinc finger.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase SLCterminal domain.
Database links:
Entrez Gene: 51428 Human
Entrez Gene: 72935 Mouse
Entrez Gene: 314336 Rat
Omim: 608170 Human
SwissProt: Q9UJV9 Human
SwissProt: Q91VN6 Mouse
Unigene: 484288 Human
Unigene: 205045 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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