background:
DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX49 (DEAD-box protein 49) is a 483 amino acid protein that contains one helicase ATP-binding domain and one helicase SLCterminal domain. One of several members of the DEAD-box protein family, DDX49 may function as a an RNA helicase that is involved in pre-mRNA splicing events.
Function:
The function of DDX49 has not yet been determined.
Similarity:
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase SLCterminal domain.
Database links:
Entrez Gene: 54555 Human
Entrez Gene: 234374 Mouse
Entrez Gene: 290660 Rat
SwissProt: Q9Y6V7 Human
SwissProt: Q3UTV0 Mouse
SwissProt: Q4FZF3 Mouse
Unigene: 143187 Human
Unigene: 388127 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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