background:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been confirmed. [provided by RefSeq, Jul 2008]
Function:
Probable ATP-binding RNA helicase.
Similarity:
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase SLCterminal domain.
Database links:
Entrez Gene: 57696 Human
Entrez Gene: 486246 Dog
Entrez Gene: 67848 Mouse
Entrez Gene: 304468 Rat
Entrez Gene: 286745 Zebrafish
SwissProt: Q8NHQ9 Human
SwissProt: Q6ZPL9 Mouse
SwissProt: Q8JHJ2 Zebrafish
Unigene: 286173 Human
Unigene: 281601 Mouse
Unigene: 16883 Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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