Rabbit Anti-DDX54/FITC Conjugated antibody

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2410015A15Rik; AI414901; ATP dependent RNA helicase DDX54; ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DDX54; DDX54_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; DEAD box protein 54; DEAD box RNA helicase 97 kDa; DP97;

Cat:

SL14353R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DDX54

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

99kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.

Subcellular Location:
Nucleus > nucleolus.

Similarity:
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase SLCterminal domain.

Database links:

Entrez Gene: 79039 Human

Omim: 611665 Human

SwissProt: Q8TDD1 Human

Unigene: 506861 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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