Home > Product > Antibody > Rabbit Anti-DEFB118/FITC Conjugated antibody
beta 118; Beta-defensin 118; Beta-defensin 118 precursor; Beta-defensin 18; C20orf63; Chromosome 20 open reading frame 63; DB118_HUMAN; DEFB-18; DEFB118; Defensin; Defensin beta 18; Defensin, beta 118; Epididymal secretory protein 13.6; epidi
Cat:
SL14249R-FITC
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human DEFB118
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
4.9kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Dec 2010]

Function:
Has antibacterial activity.

Subcellular Location:
Secreted.

Tissue Specificity:
High-level and epididymis-specific expression. Most abundant in the epithelium of the caput and is also present in the lumen and bound to sperm. Expressed also in pancreas.

Similarity:
Belongs to the beta-defensin family.

Database links:

Entrez Gene: 117285 Human

Omim: 607650 Human

SwissProt: Q96PH6 Human

Unigene: 274124 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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