Rabbit Anti-Density Regulated Protein/FITC Conjugated antibody

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denr; DENR_HUMAN; Density regulated protein; Density-regulated protein; DRP; DRP1; DRP1 protein; Protein DRP1; SMAP-3; SMAP3; Smooth muscle cell associated protein 3; Smooth muscle cell-associated protein 3.

Cat:

SL14276R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Density Regulated Protein

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

22kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]

Function:
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Tissue Specificity:
Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.

Similarity:
Belongs to the DENR family.
Contains 1 SUI1 domain.

Database links:

Entrez Gene: 8562 Human

Entrez Gene: 771794 Chicken

Entrez Gene: 614238 Cow

Entrez Gene: 68184 Mouse

Entrez Gene: 72806 Rat

Entrez Gene: 444615 Xenopus laevis

Omim: 604550 Human

SwissProt: Q5ZJ39 Chicken

SwissProt: Q2HJ47 Cow

SwissProt: O43583 Human

SwissProt: Q9CQJ6 Mouse

SwissProt: Q6GLZ1 Xenopus laevis

SwissProt: Q6DFN7 Xenopus tropicalis

Unigene: 22393 Human

Unigene: 28549 Mouse

Unigene: 7540 Xenopus laevis

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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