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Rabbit Anti-DGKB/FITC Conjugated antibody
background:
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Exhibits high phosphorylation activity for long-chain diacylglycerols.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the eukaryotic diacylglycerol kinase family.
Contains 1 DAGKc domain.
Contains 2 EF-hand domains.
Contains 2 phorbol-ester/DAG-type zinc fingers.
Database links:
Entrez Gene: 1607 Human
Entrez Gene: 21796 Mouse
Omim: 604070 Human
SwissProt: Q9Y6T7 Human
SwissProt: Q6NS52 Mouse
Unigene: 567255 Human
Unigene: 126525 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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