Home > Product > Antibody > Rabbit Anti-DGKK/FITC Conjugated antibody
142 kDa diacylglycerol kinase; DAG kinase kappa; DGK kappa; DGKK_HUMAN; Diacylglycerol kinase kappa; Diglyceride kinase kappa.
Cat:
SL14300R-FITC
Species Reactivity:
Rat,(predicted: Human,Mouse,)
Immunogen:
KLH conjugated synthetic peptide derived from human DGKK
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
142kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]

Function:
DGKK (Diacylglycerol kinase kappa) phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).

Subunit:
Does not form homooligomers.

Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein

Tissue Specificity:
Expressed in testis, and to a lesser extent in placenta.

Post-translational modifications:
Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2).

Similarity:
Belongs to the eukaryotic diacylglycerol kinase family.
Contains 1 DAGKc domain.
Contains 1 PH domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.

Database links:

Entrez Gene: 139189 Human

Entrez Gene: 331374 Mouse

SwissProt: Q5KSL6 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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