Rabbit Anti-INPP5E/FITC Conjugated antibody

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Inositol polyphosphate-5-phosphatase E; Inositol polyphosphate 5 phosphatase E; 72 kDa inositol polyphosphate 5-phosphatase; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; INP5E_HUMAN; Phosphatidylinositol polyphosphate 5-phosphatase type IV.

Cat:

SL4487R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human INPP5E

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

70kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates,inactive towards water soluble inositol phosphates.

DISEASE:
Mental retardation, truncal obesity, retinal dystrophy, and micropenis (MORMS) [MIM:610156]: An autosomal recessive disorder characterized by moderate mental retardation, truncal obesity, congenital non-progressive retinal dystrophy, and micropenis in males. The phenotype is similar to Bardet-Biedl syndrome and Cohen syndrome Distinguishing features are the age of onset, the non-progressive nature of the visual impairment, lack of dysmorphic facies, skin or gingival infection, microcephaly, mottled retina, polydactyly, and testicular anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type IV family.

Database links:

Entrez Gene: 22876 Human

Entrez Gene: 101490 Mouse

Entrez Gene: 309008 Rat

Omim: 609389 Human

SwissProt: Q9Y2H2 Human

SwissProt: Q8CDA1 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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