Rabbit Anti-DPH4/FITC Conjugated antibody

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1700030A21Rik; 2610027M02Rik; AV066965; AW240712; CSL type zinc finger containing protein 3; CSL-type zinc finger-containing protein 3; DJC24_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 24; DnaJ homolog subfamily C member 24; DNAJC24; DPH4

Cat:

SL14417R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DPH4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]

Function:
Stimulates the ATPase activity of several Hsp70-type chaperones.

Subunit:
Monomer and homooligomer. Iron binding promotes oligomerization.

Subcellular Location:
Cytoplasm, cytoskeleton (By similarity).

Similarity:
Belongs to the DPH4 family.
Contains 1 DPH-type zinc finger.
Contains 1 J domain.

Database links:

Entrez Gene: 120526 Human

Entrez Gene: 99349 Mouse

Entrez Gene: 362184 Rat

Omim: 611072 Human

SwissProt: Q6P3W2 Human

SwissProt: Q91ZF0 Mouse

Unigene: 187269 Human

Unigene: 741895 Human

Unigene: 25661 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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