Home
>
Product
>
Antibody
>
Rabbit Anti-DRG2/FITC Conjugated antibody
background:
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]
Function:
May play a role in cell proliferation, differentiation and death.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
Post-translational modifications:
Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1.
Similarity:
Belongs to the GTP1/OBG family.
Contains 1 G (guanine nucleotide-binding) domain.
Database links:
Entrez Gene: 1819 Human
Omim: 602986 Human
SwissProt: P55039 Human
Unigene: 78582 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|