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Rabbit Anti-DSCR3/FITC Conjugated antibody
background:
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
Tissue Specificity:
Ubiquitously expressed.
Similarity:
Belongs to the VPS26 family.
Database links:
Entrez Gene: 10311 Human
Omim: 605298 Human
SwissProt: O14972 Human
Unigene: 369488 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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