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Rabbit Anti-DUSP23/FITC Conjugated antibody
background:
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
Subcellular Location:
Cytoplasm; cytosol. Nucleus. Mainly cytosolic. Also nuclear.
Tissue Specificity:
Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.
Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.
Database links:
Entrez Gene: 54935 Human
Entrez Gene: 6888 Mouse
Entrez Gene: 72881 Rat
SwissProt: Q9BVJ7 Human
SwissProt: Q6NT99 Mouse
Unigene: 425801 Human
Unigene: 33024 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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