Home > Product > Antibody > Rabbit Anti-DUSP23/FITC Conjugated antibody
Dual specificity phosphatase 23; Dual specificity protein phosphatase 23; DUS23_HUMAN; Dusp23; DUSP25; EC 3.1.3.16; EC 3.1.3.48; FLJ20442; LDP 3; LDP-3; LDP3; Low molecular mass dual specificity phosphatase 3; MOSP; RP11-190A12.1; VH1 like m
Cat:
SL14456R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human DUSP23
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
17kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).

Subcellular Location:
Cytoplasm; cytosol. Nucleus. Mainly cytosolic. Also nuclear.

Tissue Specificity:
Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.

Database links:

Entrez Gene: 54935 Human

Entrez Gene: 6888 Mouse

Entrez Gene: 72881 Rat

SwissProt: Q9BVJ7 Human

SwissProt: Q6NT99 Mouse

Unigene: 425801 Human

Unigene: 33024 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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