Home > Product > Antibody > Rabbit Anti-EDDM3A/FITC Conjugated antibody
EP3A; Epididymal protein 3A; Epididymal secretory protein E3 alpha; Epididymis specific 3 alpha; FAM12A; EP3A_HUMAN; Family with sequence similarity 12 member A; HE3 ALPHA; HE3A; HE3ALPHA; Human epididymis specific 3 alpha; Human epididymis spec
Cat:
SL14499R-FITC
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human EDDM3A
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
15kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]

Function:
Possible function in sperm maturation.

Subcellular Location:
Secreted

Tissue Specificity:
Epididymis, with predominant expression in the corpus region. Moderately expressed in the vas deferens; only low levels are detectable in the caput and cauda regions.

Database links:

Entrez Gene: 10876 Human

Omim: 61316 Human

SwissProt: Q14507 Human

Unigene: 304757 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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