Rabbit Anti-EI2BL/FITC Conjugated antibody

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EI2BL; M1Pi; Mediator of RhoA-dependent invasion; Methylthioribose 1 phosphate isomerase 1; Methylthioribose 1 phosphate isomerase homolog; Methylthioribose-1-phosphate isomerase; MGC3207; MRDI; mri1; MTNA; MTNA_HUMAN; MTR-1-P isomerase; S met

Cat:

SL14530R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human EI2BL

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

39kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Subcellular Location:
Nucleus. Cytoplasm. Cell projection. Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.

Similarity:
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

Database links:

Entrez Gene: 84245 Human

Entrez Gene: 67873 Mouse

Entrez Gene: 288912 Rat

Omim: 615105 Human

SwissProt: Q2NL31 Cow

SwissProt: Q9BV20 Human

SwissProt: Q9CQT1 Mouse

SwissProt: Q5HZE4 Rat

Unigene: 439370 Human

Unigene: 278085 Mouse

Unigene: 16390 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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