Rabbit Anti-ELOVL7/FITC Conjugated antibody

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3-keto acyl-CoA synthase Elovl7; Elongation of very long chain fatty acids protein 7; ELOV7_HUMAN; ELOVL family member 7 elongation of long chain fatty acids; ELOVL family member 7 elongation of long chain fatty acids yeast; ELOVL fatty acid elongase

Cat:

SL14573R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ELOVL7

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

33kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Elongation of very long chain fatty acid-like (ELOVL) proteins are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. Fatty acids are important in many biological processes including fetal growth and development, brain development, inflammatory response, and retinal function. The ELOVL proteins function as elongases and catalyze fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 7 (ELOVL7) is involved in lipogenesis and its expression is regulated by PPAR? ELOVL7 is a 281 amino acid protein and the gene encoding ELOVL7 maps to chromosome 5q12.1.

Function:
Condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in most tissues except heart and skeletal muscle.

Similarity:
Belongs to the ELO family.

Database links:

Entrez Gene: 79993 Human

Entrez Gene: 74559 Mouse

SwissProt: A1L3X0 Human

SwissProt: Q9D2Y9 Mouse

Unigene: 274256 Human

Unigene: 286127 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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