Home > Product > Antibody > Rabbit Anti-EPB41L1/FITC Conjugated antibody
4.1N; Band 4.1 like protein 1; Band 4.1-like protein 1; DKFZp686H17242; E41L1_HUMAN; EPB41L 1; Epb41l1; Erythrocyte membrane protein band 4.1 like 1; KIAA0338; MGC11072; MRD11; Neuron type nonerythroid protein 4.1; Neuronal protein 4.1; Noner
Cat:
SL1926R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,Rhesus monkey)
Immunogen:
KLH conjugated synthetic peptide derived from human EPB41L1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
88kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Function:
May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.

Subcellular Location:
Cytoplasm; cytoskeleton.

Tissue Specificity:
Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle.

Similarity:
Contains 1 FERM domain.

Database links:

Entrez Gene: 2036 Human

Entrez Gene: 13821 Mouse

Entrez Gene: 59317 Rat

Omim: 602879 Human

SwissProt: Q9H4G0 Human

SwissProt: Q9Z2H5 Mouse

SwissProt: Q9WTP0 Rat

Unigene: 722186 Human

Unigene: 20852 Mouse

Unigene: 20361 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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