Rabbit Anti-EPS8L1/FITC Conjugated antibody

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DRC 3; DRC3; Epidermal growth factor receptor kinase substrate 8 like protein 1; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8 related protein 1; Epidermal growth factor recep

Cat:

SL14616R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human EPS8L1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

80kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

Subunit:
Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in placenta.

Similarity:
Belongs to the EPS8 family.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 54869 Human

Entrez Gene: 67425 Mouse

Entrez Gene: 361503 Rat

Omim: 614987 Human

SwissProt: Q8TE68 Human

SwissProt: Q8R5F8 Mouse

Unigene: 438862 Human

Unigene: 72392 Mouse

Unigene: 138370 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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