Rabbit Anti-ETAA1/ETAA16/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-ETAA1/ETAA16/FITC Conjugated antibody

Etaa1; ETAA1_HUMAN; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16; ETAA16.

Cat:

SL14128R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human ETAA1/ETAA16

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

103kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
ETAA16 (Ewing's tumor-associated antigen 16), also known as ETAA1, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA16 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA16 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Database links:

Entrez Gene: 54465 Human

Omim: 613196 Human

SwissProt: Q9NY74 Human

Unigene: 353022 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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