Home > Product > Antibody > Rabbit Anti-FAM5C/FITC Conjugated antibody
B830045N13Rik; BMP/retinoic acid inducible neural specific protein 3; BRINP3; BRNP3_HUMAN; DBCCR1 like protein 1; DBCCR1L; DBCCR1L1; Family with sequence similarity 5, member C; MGC107461; MGC40674; OTTMUSP00000028549; Protein FAM5C; RP11-445K1
Cat:
SL16008R-FITC
Species Reactivity:
Rat,(predicted: Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human FAM5C
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
85kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
FAM5C belongs to the FAM5 family.

Function:
Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.

Subcellular Location:
Secreted

Tissue Specificity:
Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues.

Similarity:
Belongs to the BRINP family.
Contains 1 MACPF domain.

Database links:

Entrez Gene: 339479 Human

SwissProt: Q76B58 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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