Home > Product > Antibody > Rabbit Anti-FBXW9/FITC Conjugated antibody
F box and WD 40 domain containing protein 9; F box/WD repeat containing protein 9; F-box and WD-40 domain-containing protein 9; F-box/WD repeat-containing protein 9; FBW9; FBXW9; FBXW9_HUMAN; Specificity factor for SCF ubiquitin ligase.
Cat:
SL16055R-FITC
Species Reactivity:
Human,(predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human FBXW9
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
54kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Similarity:
Contains 1 F-box domain.
Contains 7 WD repeats.

Database links:

Entrez Gene: 84261 Human

Omim: 609074 Human

SwissProt: Q5XUX1 Human

Unigene: 515154 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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