background:
Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Database links:
Entrez Gene: 222894 Human
SwissProt: Q96RJ6 Human
Unigene: 592168 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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