Rabbit Anti-FGD6/FITC Conjugated antibody

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FYVE, RhoGEF and PH domain containing protein 6; ZFYVE24; FGD6_HUMAN; Zinc finger FYVE domain containing protein 24.

Cat:

SL16082R-FITC

Species Reactivity：

(predicted: Human,Mouse,)

Immunogen：

KLH conjugated synthetic peptide derived from human FGD6

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

161kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
FGD6 is a 1,430 amino acid cytoplasmic protein that belongs to the FGD family and exists as two alternatively spliced isoforms. Thought to activate Cdc42 by exchanging bound GDP for free GTP, FGD6 is also implicated in maintenance of the actin cytoskeleton and regulating cell shape. Encoded by a gene that maps to human chromosome 12q22, FGD6 contains one FYVE-type zinc finger, two PH domains and a single DH (DBL-homology) domain.

Function:
FGD6 may activate CDC42 by exchanging bound GDP for free GTP. It may also play a role in regulating the actin cytoskeleton and cell shape. There are two isoforms.

Subcellular Location:
Cytoplasm (Probable). Cytoplasm, cytoskeleton (Probable).

Database links:

Entrez Gene: 55785 Human

SwissProt: Q6ZV73 Human

Unigene: 506381 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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