Rabbit Anti-FMO4/FITC Conjugated antibody

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Flavin containing monooxygenase 4; Dimethylaniline monooxygenase [N oxide forming] 4; Dimethylaniline monooxygenase [N-oxide-forming] 4; Dimethylaniline monooxygenase 4; Dimethylaniline oxidase 4; FMO 2; FMO 4; FMO2; Fmo4; FMO4_HUMAN; Hepatic fla

Cat:

SL16099R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human FMO4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

63kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Sep 2013]

Function:
This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.

Subcellular Location:
Microsome membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Liver.

Similarity:
Belongs to the FMO family.

Database links:

Entrez Gene: 2329 Human

Omim: 136131 Human

SwissProt: P31512 Human

Unigene: 386502 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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