Rabbit Anti-CXorf34/TRMT2B/FITC Conjugated antibody

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FLJ12687; Chromosome X open reading frame 34; CXorf34; dJ341D10.3; FLJ12687; Putative methyltransferase CXorf34; TRM2 homolog; TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae); TRM2 tRNA methyltransferase 2 homolog B; TRM2_HUMAN; TRMT2B;

Cat:

SL16104R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human CXorf34

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

56kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]

Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation.

Similarity:
Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family.

Database links:

Entrez Gene: 79979 Human

GenBank: NM_024917 Human

SwissProt: Q96GJ1 Human

Unigene: 496501 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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