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Rabbit Anti-FLJ36733/FITC Conjugated antibody
background:
This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]
Function:
Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.
Subcellular Location:
Mitochondrion.
DISEASE:
Defects in TACO1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.
Similarity:
Belongs to the TACO1 family.
Database links:
Entrez Gene: 51204 Human
Omim: 612958 Human
SwissProt: Q9BSH4 Human
Unigene: 174134 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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