background:
This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive
Function:
Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol-4,5-bisphosphate.
Subcellular Location:
Cell projection > dendritic spine.
Similarity:
Contains 1 FERM domain.
Contains 1 PDZ (DHR) domain.
Contains 1 WW domain.
Database links:
http://www.ncbi.nlm.nih.gov/protein/121948742
UniProtKB/Swiss-Prot: Q14CM0.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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