Rabbit Anti-FRYL/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-FRYL/FITC Conjugated antibody

2010313D22Rik; 2310004H21Rik; 2510002A14Rik; 9030227G01Rik; AF4P12; AI930088; ALL fused gene from chromosome 4p12; ALL1-fused gene from chromosome 4p12 protein; DKFZp686E205; FLJ161772; FRYL_HUMAN; FRY like; Furry homolog like (Drosophila); Fu

Cat:

SL16184R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human FRYL

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

339kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
FRYL plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis. It regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. FRYL May function as a transcriptional activator.

Function:
Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator.

Tissue Specificity:
Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin.

DISEASE:
Note=A chromosomal aberration involving FRYL is found in treatment-related acute lymphoblastic leukemia (ALL). Translocation t(4;11)(p12;q23) that forms a KMT2A/MLL1-FRYL fusion protein.

Similarity:
Belongs to the furry protein family.

Database links:

Entrez Gene: 285527 Human

Entrez Gene: 72313 Mouse

SwissProt: O94915 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall