background:
GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]
Function:
Orphan receptor.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:
Entrez Gene: 10936 Human
Entrez Gene: 237716 Mouse
Omim: 606704 Human
SwissProt: O95800 Human
SwissProt: Q6X632 Mouse
Unigene: 40763 Human
Unigene: 338361 Mouse
Unigene: 484157 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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