background:
GPR153 (G protein-coupled receptor 153), also known as PGR1, is a 609 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. The gene encoding GPR153 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Function:
Orphan receptor.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:
Entrez Gene: 387509 Human
Entrez Gene: 518906 Cow
Entrez Gene: 489630 Dog
Entrez Gene: 100408544 Marmoset (common)
Entrez Gene: 100129 Mouse
Entrez Gene: 619550 Rat
Omim: 614269 Human
SwissProt: Q6NV75 Human
SwissProt: Q8K0Z9 Mouse
Unigene: 531581 Human
Unigene: 23235 Mouse
Unigene: 198305 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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