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Rabbit Anti-HAO2/FITC Conjugated antibody
background:
This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed predominantly in liver and kidney and has the highest activity toward the substrate 2-hydroxypalmitate. Two alternatively spliced variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
Function:
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids.
Subcellular Location:
Peroxisome.
Tissue Specificity:
Liver and kidney.
Similarity:
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Contains 1 FMN hydroxy acid dehydrogenase domain.
Database links:
Entrez Gene: 51179 Human
Omim: 605176 Human
SwissProt: Q9NYQ3 Human
Unigene: 659767 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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