background:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity).
Subcellular Location:
Membrane; Single-pass membrane protein
Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Database links:
Entrez Gene: 283450 Human
SwissProt: Q9Y4D8 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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