Rabbit Anti-TOR3A/ADIR2/FITC Conjugated antibody

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ADIR; ADIR2; ATP dependant interferon response protein 1; ATP dependant interferon responsive; ATP dependent interferon responsive protein; ATP-dependent interferon-responsive protein; FLJ22345; MGC111104; Tor3a; TOR3A_HUMAN; torsin 3A; Torsin

Cat:

SL16611R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TOR3A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

43kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Torsin3A is a 397 amino acid member of the clpA/clpB family of proteins. Localized to the cytoplasm and the endoplasmic reticulum, Torsin3A is most highly expressed in stomach, lymph nodes and salivary glands. Torsin3A contains a hydrophobic N-terminal sequence, an ATP binding domain and 8 putative phosphorylation sites. Highly homologous with TorsinA and TorsinB, Torsin3A is thought to be related to the AAA chaperone-like family of ATPases. Members of this family play a role in the assembly, disassembly and operation of a variety of protein complexes, confer increased tolerance to high temperature and promote specific proteolysis. Torsin3A is also referred to as an interferon responsive gene, as interaction with type 1 interferons (IFN-alpha and IFN-beta) cause a 5 to 40 fold increase in Torsin3A mRNA levels. Three isoforms of Torsin3A exist as a result of alternative splicing events, and isoform 2 is expressed exclusively in the placenta

Subcellular Location:
Cytoplasm. Endoplasmic reticulum.

Tissue Specificity:
Ubiquitously expressed. Highest expression in stomach, salivary glands and lymph nodes. Isoform 2 is expressed in placenta.

Similarity:
Belongs to the clpA/clpB family. Torsin subfamily.

Database links:

Entrez Gene: 64222 Human

Entrez Gene: 30935 Mouse

Entrez Gene: 304884 Rat

Omim: 607555 Human

SwissProt: Q9H497 Human

SwissProt: Q9ER38 Mouse

SwissProt: Q5M936 Rat

Unigene: 584957 Human

Unigene: 206737 Mouse

Unigene: 2164 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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