Rabbit Anti-KLRC3/FITC Conjugated antibody

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Killer cell lectin like receptor subfamily C member 3; KLRC 3; KLRC3; NK cell receptor E; NKG2 E activating NK receptor; NKG2 E; NKG2 E type II integral membrane protein; NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NK

Cat:

SL16781R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human KLRC3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

27kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (SLCtype) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a SLCtype lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several SLCtype lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subcellular Location:
Membrane.

Tissue Specificity:
Natural killer cells.

Similarity:
Contains 1 SLCtype lectin domain.

Database links:

Entrez Gene: 3823 Human

Entrez Gene: 58179 Mouse

Entrez Gene: 500338 Rat

Omim: 602892 Human

SwissProt: Q07444 Human

Unigene: 654362 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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