Rabbit Anti-KTEL1/FITC Conjugated antibody

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C3orf9; CAP10 like 46 kDa protein; CAP10 like protein, 46 kDa; CLP46; hCLP46; KDELC family like 1; KDELCL1; KTEL (Lys Tyr Glu Leu) containing 1; KTEL motif containing protein 1; KTELC1; MDS010; MDSRP; myelodysplastic syndromes relative protein

Cat:

SL16861R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human KTEL1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

43kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the SLCterminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most adult tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94% and 91% sequence similarity with its bovine and mouse homologs, respectively.

Function:
UDP-glucosyltransferase.

Subcellular Location:
Endoplasmic reticulum lumen.

Tissue Specificity:
Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine.

Similarity:
Belongs to the glycosyltransferase 90 family.

Database links:

Entrez Gene: 56983 Human

Entrez Gene: 224143 Mouse

Entrez Gene: 217691 Rat

SwissProt: Q8NBL1 Human

SwissProt: Q8BYB9 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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