Rabbit Anti-KCNH6/FITC Conjugated antibody

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eag related protein 2; ERG 2; ERG2; ether a go go related gene potassium channel 2; HERG2; Kv11.2; potassium voltage gated channel subfamily H (eag-related), member 6; Voltage-gated potassium channel subunit Kv11.2.

Cat:

SL16887R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human KCNH6

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

110kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly.

Subunit:
The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimers with KCNH2/ERG1 and KCNH7/ERG3 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in prolactin-secreting adenomas.

Similarity:
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily.
Kv11.2/KCNH6 sub-subfamily.
Contains 1 cyclic nucleotide-binding domain.
Contains 1 PAC (PAS-associated SLCterminal) domain.
Contains 1 PAS (PER-ARNT-SIM) domain.

Database links:

Entrez Gene: 81033 Human

Entrez Gene: 192775 Mouse

Entrez Gene: 116745 Rat

Omim: 608168 Human

SwissProt: Q9H252 Human

SwissProt: O54853 Rat

Unigene: 591177 Human

Unigene: 343850 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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