background:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]
Function:
Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.
Subcellular Location:
Membrane.
Tissue Specificity:
Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Database links:
Entrez Gene: 60598 Human
Entrez Gene: 241769 Mouse
Entrez Gene: 156873 Rat
Omim: 607368 Human
SwissProt: Q9H427 Human
SwissProt: Q8R5I0 Rat
Unigene: 528664 Human
Unigene: 295337 Mouse
Unigene: 161865 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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