Rabbit Anti-KCNK5/FITC Conjugated antibody

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Acid sensitive potassium channel protein TASK 2; Acid-sensitive potassium channel protein TASK-2; FLJ11035; K2p5.1; KCNK 5; KCNK5; KCNK5_HUMAN; Potassium channel subfamily K member 1; Potassium channel subfamily K member 5; TASK 2; TASK2; TWIK

Cat:

SL16904R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human KCNK5

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

56kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]

Function:
pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.

Subcellular Location:
Membrane.

Tissue Specificity:
Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.

Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Database links:

Entrez Gene: 8645 Human

Entrez Gene: 16529 Mouse

Omim: 603493 Human

SwissProt: O95279 Human

SwissProt: Q9JK62 Mouse

Unigene: 444448 Human

Unigene: 68998 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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