Rabbit Anti-KCNS3/FITC Conjugated antibody

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Delayed rectifier K(+) channel alpha subunit 3; Delayed rectifier K+ channel alpha subunit 3; Delayed-rectifier K(+) channel alpha subunit 3; KCNS 3; Kcns3; KCNS3_HUMAN; KV 9.3; KV9.3; MGC9481; Potassium voltage gated channel delayed rectifier pr

Cat:

SL16918R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Pig,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human KCNS3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

56kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]

Function:
Potassium channel subunit. Modulates channel activity and reduces the ion flow.

Subunit:
Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins (By similarity).

Subcellular Location:
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.

Tissue Specificity:
Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.

Similarity:
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.

Database links:

Entrez Gene: 3790 Human

Entrez Gene: 47676 Mouse

Entrez Gene: 83588 Rat

Omim: 603888 Human

SwissProt: Q9BQ31 Human

SwissProt: Q8BQZ8 Mouse

SwissProt: O88759 Rat

Unigene: 414489 Human

Unigene: 113278 Mouse

Unigene: 10878 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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