Rabbit Anti-KCNS2/FITC Conjugated antibody

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Delayed rectifier K(+) channel alpha subunit 2; Delayed-rectifier K(+) channel alpha subunit 2; Kcns2; KCNS2_HUMAN; KIAA1144; KV9.2; Potassium voltage gated channel subfamily S member 2; Potassium voltage-gated channel subfamily S member 2; Voltage gated

Cat:

SL16917R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human KCNS2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

54kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming ?subunits (KV), which include the KV1, KV2, KV3, KV4 and KV9 proteins, and accessory or KSLVsubunits that modify the gating properties of the coexpressed KV subunits. KV9.2 is a K+ channel subunit that reduces the ion flow and regulates channel activity. It localizes to the cell membrane and, in the absence of KCNB1, KV9.2 may not reach the plasma membrane and may remain in an intracellular compartment.

Function:
Potassium channel subunit. Modulates channel activity and reduces the ion flow.

Subcellular Location:
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.

Tissue Specificity:
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.2/KCNS2 sub-subfamily.

Database links:

Entrez Gene: 3788 Human

Entrez Gene: 16539 Mouse

Entrez Gene: 66022 Rat

Omim: 602906 Human

SwissProt: Q9ULS6 Human

SwissProt: O35174 Mouse

SwissProt: Q9ER26 Rat

Unigene: 317645 Human

Unigene: 71045 Mouse

Unigene: 64498 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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