Home > Product > Antibody > Rabbit Anti-KIAA1191/FITC Conjugated antibody
IR2155535; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; P33MX_HUMAN; Transmembrane protein 2 like; Putative monooxygenase p33MONOX; Brain-derived rescue factor p60MONOX; Flavin monooxygenase motif-containing protein of 33 kDa.
Cat:
SL16994R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human KIAA1191
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
33kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
KIAA1199 belongs to the TMEM2 family and contains 4 PbH1 repeats. It is expressed in the inner ear. It is expressed in cochlea and vestibule tissues and it may be involved in hearing. Defects in KIAA1199 may be a cause of non-syndromic hearing loss. It is also thought that KIAA1199 is a tumor suppressor that may be involved in establishing cellular mortality in normal human cells.

Function:
Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

Subunit:
Interacts with COBRA1, NOL12 and PRNP.

Tissue Specificity:
Down-regulated in the occipital lobe of an early stage Alzheimer disease patients.

Similarity:
Belongs to the P33MONOX family.

Database links:

Entrez Gene: 57179 Human

SwissProt: Q96A73 Human

Unigene: 519783 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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