Rabbit Anti-G2E3/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-G2E3/FITC Conjugated antibody

KIAA1333 FLJ20333; G2/M phase specific E3 ubiquitin protein ligase; G2E3; PHF7B. G2E3_HUMAN

Cat:

SL17000R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human G2E3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

80kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
KIAA1333 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Essential in early embryonic development to prevent apoptotic death.

Subcellular Location:
Nucleus, nucleolus. Cytoplasm. Note: Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage.

Tissue Specificity:
Predominantly expressed in brain, liver, kidney, testes and ovary.

Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-proteinligase) domain.
Contains 3 PHD-type zinc fingers.

Database links:

Entrez Gene: 55632 Human

Omim: 611299 Human

SwissProt: Q7L622 Human

SwissProt: Q5RJY2 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall