Rabbit Anti-Kinesin 5C/NKHC2/FITC Conjugated antibody

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FLJ44735; KIAA0531; KIF 5C; KIF5C; KIF5C protein; KIF5C_HUMAN; Kinesin family member 5C; Kinesin heavy chain isoform 5C; Kinesin Heavy Chain Neuron Specific 2; Kinesin heavy chain neuron specific; Kinesin heavy chain neuron-specific 2; Kinesin5

Cat:

SL17065R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Kinesin 5C/NKHC2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

109kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Neuronal kinesin heavy chain 2 (NKHC2) is a 1,032 amino acid protein that is part of the kinesin superfamily which consists of the heavy chains of conventional kinesin. NKHC is expressed throughout the central nervous system, but is highly expressed in certain subsets of neurons. NKHC has a unique SLCterminal stretch of 69 amino acids and interacts with dystrobrevin, an adaptor/scaffolding protein. This interaction may play a role in the transport and targeting of components of the dystrophin-associated protein complex to precice sites in the cell. NKHC may also be involved in the microtubule-dependent slow axonal transport of neurofilament proteins during the maturation of neuronal cells.

Function:
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.

Subunit:
Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 and KLC3 (By similarity). Interacts with TRAK1.

Subcellular Location:
Cytoplasm； cytoskeleton.

Tissue Specificity:
Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary.

Similarity:
Belongs to the kinesin-like protein family. Kinesin subfamily.
Contains 1 kinesin-motor domain.

Database links:

Entrez Gene: 3800 Human

Omim: 604593 Human

SwissProt: O60282 Human

SwissProt: P56536 Rat

Unigene: 435557 Human

Unigene: 660699 Human

Unigene: 50843 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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